{Reference Type}: Case Reports {Title}: Case series of the inferior vena cava primary leiomyosarcoma treatment. {Author}: Lazar D;Stefan D;Marko D;Zlatanovic P;Sladojevic M;Ilijas C;Grubor N;Andreja D; {Journal}: J Surg Case Rep {Volume}: 2024 {Issue}: 6 {Year}: 2024 Jun 暂无{DOI}: 10.1093/jscr/rjad546 {Abstract}: Tumors of the inferior vena cava (IVC) are rare and usually malignant and they can be primary and secondary. The most common primary tumor of the IVC is primary leiomyosarcoma. The first case of primary IVC leiomyosarcoma has been described in 1871 [1].The total number of 218 cases has collected until 1996 [2]. After that, three large single center series of these tumors emerged [3-5]. Present a series of five cases of these tumors. All the patients underwent a wide complete resection of tumors and the reconstruction with Dacron grafts. One patient died 19 months after the surgery, while the remaining ones survived without a local and system disease relapse. Although a surgical resection combined with the chemotherapy is often not curative, it can achieve a significant long-term survival. For this reason, we recommend the aggressive surgical management using the modern vascular surgical and oncology techniques.