{Reference Type}: Case Reports {Title}: Diagnosis and Management of Riga-Fede Disease: A Case Series. {Author}: Nguyen CG;Wikner EE;Gallagher TQ;Birsch LA;Darrow DH; {Journal}: Laryngoscope {Volume}: 0 {Issue}: 0 {Year}: 2024 Jun 5 {Factor}: 2.97 {DOI}: 10.1002/lary.31547 {Abstract}: In this case series, we present four unique cases of Riga-Fede disease (RFD), a rare disorder characterized by mucosal trauma as a result of repetitive tongue protrusion against the incisors, leading to the development of a large oral mass/ulceration. Due to the rapid development and growth of these lesions mimicking malignancy, it is important for the general and pediatric otolaryngologist to correctly diagnose and treat this benign disorder. This series highlights the variable clinical presentations, along with comorbidities of RFD, as well as the importance of interdisciplinary care between the pediatric otolaryngologist and pediatric dentist in its management. Laryngoscope, 2024.