{Reference Type}: Case Reports {Title}: Unilateral Periorbital Swelling in a Pediatric Patient. {Author}: Rosas Herrera A;Parker AB;Chaskes M;Askin F;Monk AS;Stephens JR;Thorp BD;Ebert CS;Senior BA;Kimple AJ;Kong KA; {Journal}: Clin Med Insights Case Rep {Volume}: 17 {Issue}: 0 {Year}: 2024 暂无{DOI}: 10.1177/11795476241255563 {Abstract}: Infratemporal fossa (ITF) tumors are rare in children and may present with a variety of symptoms. Teratomas are neoplasms derived from the 3 germ layers and approximately 6% to 10% are within the head and neck. Our study discusses one of the first reported cases of teratoma in the ITF in a pediatric patient. A 3-year-old girl presents with 2 years of recurrent monthly left periorbital swelling accompanied by fevers, skin discoloration, and pain. Prior episodes were treated with antibiotics with incomplete resolution. Imaging revealed a cystic lesion centered in the ITF. She was taken for endoscopic endonasal biopsy of the lesion and had no complications. Pathology revealed a mature teratoma composed primarily of pancreatic tissue. Providers should consider masses such as teratoma in the differential for ITF tumors and periorbital edema unresponsive to typical treatment.