{Reference Type}: Journal Article
{Title}: When Lightning Strikes Twice: Routes to Second Malignancies in Young Patients.
{Author}: Pacyna CN;Nangalia J;
{Journal}: Cancer Discov
{Volume}: 14
{Issue}: 6
{Year}: 2024 Jun 3
{Factor}: 38.272
{DOI}: 10.1158/2159-8290.CD-24-0325
{Abstract}: <B>UNASSIGNED: </B>Given the rarity of cancer in childhood, it should be even more uncommon for pediatric cancer survivors to develop a second, independent malignancy, yet they incur a greatly elevated risk after initial remission. In this issue of Cancer Discovery, Sánchez-Guixé and colleagues unpick the origins of second tumours in four children, and the potential role platinum-based chemotherapy may play in subsequent tumorigenesis. See related article by Sánchez-Guixé et al., p. 953 (8).