{Reference Type}: Journal Article
{Title}: Performance of Cepheid CT/NG Xpert rapid PCR test for detection of Chlamydia trachomatis and Neisseria gonorrhoeae at a tertiary care centre in North India.
{Author}: Sethi S;Gudisa R;Sharma N;Sreenivasan P;Gupta P;Chaudary H;Narang T;Bagga R;
{Journal}: Indian J Med Microbiol
{Volume}: 50
{Issue}: 0
{Year}: 2024 Jul-Aug 7
{Factor}: 1.347
{DOI}: 10.1016/j.ijmmb.2024.100639
{Abstract}: <B>BACKGROUND: </B>Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) are prevalent causes of sexually transmitted infections (STIs) globally, leading to substantial morbidity and transmission risks.<BR><B>METHODS: </B>This study evaluates the diagnostic efficacy of Xpert CT/NG compared to conventional PCR and culture methods in 121 patients at a tertiary care centre in North India.<BR><B>RESULTS: </B>Xpert CT/NG demonstrated high sensitivity (85.8%) and specificity (96.3%) outperforming conventional PCR. Xpert CT/NG's rapidity and accuracy underscore its utility in timely diagnosis and control of STIs.<BR><B>CONCLUSIONS: </B>As sexually transmitted infections pose a serious health concern implementation of such rapid diagnostic methods/point of care testing methods are to be implemented for early diagnosis.