{Reference Type}: Journal Article
{Title}: Risk Factors for Retinal Detachment in Marfan Syndrome After Pediatric Lens Removal.
{Author}: Abdelmassihm Y;Lecoge R;El Hassani M;Dureau P;Caputo G;Metge F;Chapron T;
{Journal}: Am J Ophthalmol
{Volume}: 266
{Issue}: 0
{Year}: 2024 May 30
{Factor}: 5.488
{DOI}: 10.1016/j.ajo.2024.05.003
{Abstract}: <B>OBJECTIVE: </B>To determine retinal detachment (RD) risk factors after lens removal surgery in children with Marfan syndrome (MS).<BR><B>METHODS: </B>Retrospective, case control study.<BR><B>METHODS: </B>This was an institutional case series including children (age <18 years) with MS who underwent lens removal surgery. Clinical and surgical characteristics were extracted from the children's electronic files: age, axial length (AL), gender, number of surgeries received, intraocular lens (IOL) implantation at the first surgery, complete removal of the capsular bag, and final best-corrected visual acuity. Risk factors associated with RD occurrence were identified.<BR><B>RESULTS: </B>Among 158 eyes included (85 children), 35 eyes (22.2%) developed RD during follow-up. Bilateral detachment occurred in 11 patients (45.8%). Age at the time of the lens removal surgery was not different between groups. Children in the RD group had a higher AL (P < .001), longer follow-up, IOL implantation, and capsular residue. Multivariate analysis identified capsular residue (odds ratio, 16.8; 95% CI, 1.9-148.8; P = .01) and AL (odds ratio, 1.3; 95% CI, 1.01-1.7; P = .03) as predictors for RD.<BR><B>CONCLUSIONS: </B>Children with MS and increased AL were more likely to develop an RD after lens surgery. When considering lens removal surgery in a pediatric population presenting with MS, a complete capsular removal seemed to be the safer option regarding RD risk.