{Reference Type}: Journal Article
{Title}: Distribution of pufferfish saxitoxin- and tetrodotoxin-binding protein homolog and tetrodotoxin in the brain and pituitary of juvenile tiger puffer Takifugu rubripes.
{Author}: Amano M;Amiya N;Otsuka Y;Homma J;Hagio H;Takatani T;Yamamoto N;Yamaguchi K;Sakakura Y;
{Journal}: Toxicon
{Volume}: 246
{Issue}: 0
{Year}: 2024 Aug 2
{Factor}: 3.035
{DOI}: 10.1016/j.toxicon.2024.107777
{Abstract}: Pufferfish saxitoxin- and tetrodotoxin (TTX)-binding protein (PSTBP) is considered to transfer TTX between tissues. The immunohistochemical distribution of PSTBP-homolog (PSTBPh) and TTX in the brain and pituitary of hatchery-reared juvenile tiger puffer Takifugu rubripes was investigated. PSTBPh was observed mainly in the pars intermedia of the pituitary. TTX was only detected in a TTX-fed fish in the neurohypophysis of the pituitary and in several other brain regions. The relationship between PSTBPh and TTX is discussed.