{Reference Type}: Journal Article
{Title}: Advances in combined neuroendocrine carcinoma of lung cancer.
{Author}: Han Z;Yang F;Wang F;Zheng H;Chen X;Meng H;Li F;
{Journal}: Pathol Oncol Res
{Volume}: 30
{Issue}: 0
{Year}: 2024
{Factor}: 2.874
{DOI}: 10.3389/pore.2024.1611693
{Abstract}: Lung cancer incidence and mortality rates are increasing worldwide, posing a significant public health challenge and an immense burden to affected families. Lung cancer encompasses distinct subtypes, namely, non-small-cell lung cancer (NSCLC) and small-cell lung cancer (SCLC). In clinical investigations, researchers have observed that neuroendocrine tumors can be classified into four types: typical carcinoid, atypical carcinoid, small-cell carcinoma, and large-cell neuroendocrine carcinoma based on their unique features. However, there exist combined forms of neuroendocrine cancer. This study focuses specifically on combined pulmonary carcinomas with a neuroendocrine component. In this comprehensive review article, the authors provide an overview of combined lung cancers and present two pathological images to visually depict these distinctive subtypes.