{Reference Type}: Journal Article {Title}: What Happens When the Zygote Divides? On the Metaphysics of Monozygotic Twinning. {Author}: Skrzypek JW; {Journal}: J Med Philos {Volume}: 49 {Issue}: 4 {Year}: 2024 Jul 11 {Factor}: 1.493 {DOI}: 10.1093/jmp/jhae022 {Abstract}: It is often argued that certain metaphysical complications surrounding the phenomenon of monozygotic twinning force us to conclude that, prior to the point at which twinning is no longer possible, the zygote or early embryo cannot be considered an individual human organism. In this essay, I argue, on the contrary, that there are in fact several ways of making sense of monozygotic twinning that uphold the humanity of the original zygote, but also that there is no easy answer to what happens when the human zygote twins. All of the options available carry with them one or more surprising, alarming, or otherwise counterintuitive implications. All things considered, I conclude that the "budding option," according to which the original human organism present before twinning carries on as one of the resulting embryos but not the other, is the most plausible explanation of what happens when a human zygote twins.