{Reference Type}: Case Reports
{Title}: Primary mediastinal choriocarcinoma requiring differentiation from non-small cell lung cancer: An autopsy case report.
{Author}: Matsuyama T;Kubota K;Tsuruzono K;Uchida H;Hamasaki T;Mizuno K;Inoue H;
{Journal}: Respir Med Case Rep
{Volume}: 50
{Issue}: 0
{Year}: 2024
暂无{DOI}: 10.1016/j.rmcr.2024.102037
{Abstract}: A 65-year-old man with dyspnea and hemoptysis presented with a right upper lobe mass associated with enlarged mediastinal lymph nodes and bilateral pulmonary nodules on chest computed tomography (CT), suspected lung cancer. Bronchial and CT-guided biopsies revealed poorly differentiated carcinoma. His condition deteriorated rapidly before a definitive diagnosis could be made. Autopsy revealed primary mediastinal choriocarcinoma. Primary mediastinal choriocarcinomas are rare, difficult to diagnose early and have a poor prognosis. In patients with a tumor expanding across the lung and mediastinum and exhibiting pathologic findings of a pooly differentiated carcinoma, we should consider choriocarcinoma, evaluating the serum β-human chorionic gonadotropin levels.