{Reference Type}: Case Reports {Title}: Multinodular goiter with a retropharyngeal extension: A report of two cases and literature review. {Author}: Alqahtani SM;Alwohaibi RN;Alahmari MS;Almuhaimid TM; {Journal}: J Family Community Med {Volume}: 31 {Issue}: 2 {Year}: 2024 Apr-Jun 暂无{DOI}: 10.4103/jfcm.jfcm_263_23 {Abstract}: Multinodular goiter (MNG) is a chronic benign nodular enlargement of the thyroid gland. It presents as an anterior painless neck mass, potentially progressing to exert pressure on the trachea and esophagus and giving rise to compressive symptoms. MNG is a common thyroid gland disorder; however, retropharyngeal goiter is considered rare with few reported cases. We report the cases of two patients who presented to our institution with MNG with retropharyngeal extension: a 62-year-old female patient who presented with a progressive anterior neck mass with dilated neck veins; and a 49-year-old male who presented with a painless anterior neck mass. Both patients successfully underwent total thyroidectomy with an uneventful postoperative recovery. The clinical presentation of MNG with retropharyngeal extension varies with patients; hence, a high index of suspicion is of the utmost significance. While the retropharyngeal extension does not cause compressive symptoms, it should raise the suspicion of a large retrosternal component.