{Reference Type}: Case Reports {Title}: Endogenous Endophthalmitis from Urinary Tract Infection Caused by Group B Streptococcus: A Case Report. {Author}: You H;Kim J; {Journal}: Medicina (Kaunas) {Volume}: 60 {Issue}: 5 {Year}: 2024 Apr 25 {Factor}: 2.948 {DOI}: 10.3390/medicina60050700 {Abstract}: We present a case of endogenous endophthalmitis with urinary tract infection (UTI) caused by group B Streptococcus (GBS). An 86-year-old female initially presented with ocular pain and sudden visual disturbance of the left eye. The patient did not complain of other symptoms and had no history of recent ocular surgery or trauma. Endogenous endophthalmitis was clinically diagnosed based on ophthalmic examination, history, and lab results showing systemic infection. A few days later, GBS was identified in her aqueous humor, blood, and urine cultures. Intravitreal ceftazidime and vancomycin injections, as well as fortified ceftazidime and vancomycin eye drops, were used immediately after clinical diagnosis. However, the symptoms worsened despite repeated intravitreal injections, so evisceration was performed. Endogenous endophthalmitis caused by GBS is very virulent and may present without evident systemic symptoms. The early recognition of the disease and systemic work up, followed by prompt treatment, is necessary.