{Reference Type}: Journal Article {Title}: Breadth of substance use is associated with the selection of a larger food portion size via elevated impulsivity. {Author}: Nolan LJ;Embling R;Wilkinson LL; {Journal}: Physiol Behav {Volume}: 283 {Issue}: 0 {Year}: 2024 Sep 1 {Factor}: 3.742 {DOI}: 10.1016/j.physbeh.2024.114594 {Abstract}: Substance use is associated with altered or elevated food consumption and disordered eating. In the present study we examined whether breadth (variety) of drug use was associated with elevated portion size in a general population sample as it was in persons in recovery from substance use disorder. Furthermore, measures of emotional eating, impulsivity, food misuse, food craving were taken as possible mediators and reward responsiveness was examined as a potential moderator of this association. 444 adults (48.6 % women, mean age of 47.8 years) completed an online study in which they were asked to make judgements of ideal portion size for 6 different foods using a validated online tool that allowed participants to adjust the portion size of images of foods. Ideal portion size has been identified as a strong predictor of actual consumption. Participants were also asked to report the number of substances used in the past and provide anthropometric information. The results confirmed that breadth of drug use was associated with selection of higher portion size. Reward responsiveness was not a moderator of this relationship. Of the tested mediators, only impulsivity mediated the association between breadth of drug use and portion size. The results show that impulsivity may underlie the association between eating and substance use.