{Reference Type}: Case Reports
{Title}: Mastering bladder paraganglioma for optimal treatment: a case report of robot-assisted surgery.
{Author}: Orsini A;Ferretti S;Tamborino F;Cicchetti R;Ciavarella D;Seccia B;Basilico R;Colasante A;Marchioni M;Schips L;
{Journal}: Ther Adv Urol
{Volume}: 16
{Issue}: 0
{Year}: 2024 Jan-Dec
{Factor}: 3.13
{DOI}: 10.1177/17562872241249603
{Abstract}: Bladder paraganglioma is a rare neuroendocrine neoplasm, either functional or non-functional, arising from the urinary bladder. Functional variants present with catecholamine-related symptoms, while non-functional variants pose diagnostic challenges, mimicking urothelial carcinoma. Misdiagnosis risks underscore the importance of accurate identification for appropriate patient management. In this case, a 52-year-old man, diagnosed incidentally with hypertension and reported occasional post-micturition tachycardia, underwent abdominal ultrasound for known hepatic cyst follow-up, revealing an oval hypoechoic bladder mass. Initial consideration of bladder urothelial carcinoma prompted further investigation with contrast-enhanced CT scan and cystoscopy that confirmed extrinsic mass nature, and subsequent robotic-assisted partial cystectomy was performed. Histologically, the removed mass exhibited characteristic features of bladder paraganglioma. Postoperative recovery was uneventful, with resolution of post-micturition tachycardia at 1 month. Follow-up includes endocrinological evaluation and a 6-month CT scan. In conclusion, bladder paraganglioma should be considered in para-vesical mass differentials. This case highlights the importance of meticulous history collection, even in asymptomatic patients, the need for a multidisciplinary approach for accurate diagnosis and management of this rare condition, and the robotic approach as a viable option.