{Reference Type}: Case Reports
{Title}: Pyogenic liver abscess caused by an atypical hypervirulent Klebsiella pneumoniae K1-ST23 in Mexico.
{Author}: Martínez-Hernandez L;Alvarado-Delgado A;Rodríguez-Medina N;Garcia-Peniche J;Donis-Hernández JJ;Perez-Rezendiz OA;Nava-Domínguez N;Duarte-Zambrano L;Tamayo-Legorreta EM;Garza-Ramos U;
{Journal}: IDCases
{Volume}: 36
{Issue}: 0
{Year}: 2024
暂无{DOI}: 10.1016/j.idcr.2024.e01987
{Abstract}: Hypervirulent K. pneumoniae infection has been raising worldwide and is one of the major causes of community-acquired pyogenic liver abscess. We described a case report of pyogenic liver abscess caused by an atypical hypervirulent (non-hypermucoviscous) K. pneumoniae K1 ST23 in a diabetic Asian patient who resided in Mexico. The susceptibility to antimicrobials, pathogenicity, molecular and genomic analysis were determined. A man from Guangdong (China) with a recent diagnosis of diabetes mellitus was admitted to the hospital, and he denied traveling in the last 3 months. A computed tomography revealed a right lobe liver abscess. On the third day after admission a Klebsiella pneumoniae isolate (14652) was obtained. The isolate corresponded to a susceptible K. pneumoniae with capsular type K1 and ST23 (CG23) and exhibited a non-hypermucoviscous phenotype. The isolate 14652 was genetically related to the globally distributed lineage ST23-KL1. This study describes the first case in Mexico of K. pneumoniae capsular type K1 and ST23 with an atypical hypervirulent phenotype.