{Reference Type}: Journal Article {Title}: A rare case report of bilateral vestibulopathy due to otosyphilis. {Author}: Gu H;Xu Y;Xu J;Zhuang J; {Journal}: Medicine (Baltimore) {Volume}: 103 {Issue}: 20 {Year}: 2024 May 17 {Factor}: 1.817 {DOI}: 10.1097/MD.0000000000038149 {Abstract}: BACKGROUND: Bilateral vestibulopathy is an important cause of imbalance. There are multiple etiologies of bilateral vestibulopathy (BVP), but reports of BVP due to otosyphilis are rare.
METHODS: A 39-year-old male was referred to our medical center due to vertigo, persistent dizziness and gait disturbance for 2 months.
METHODS: Bilateral vestibulopathy due to otosyphilis was considered in this case, as confirmed through analyses of vestibular function, laboratory tests, and penicillin treatment.
METHODS: The patient was was treated with a high dose of penicillin G (24 × 106 IU/d) for 14 days.
RESULTS: The patient's symptoms had improved greatly following treatment, with dizziness and gait disturbance having completely resolved at 3 months following hospital discharge.
CONCLUSIONS: Bilateral vestibulopathy should be considered when evaluating patients with acute or subacute persistent dizziness. Clinicians should also be aware of the potential for otosyphilis among patients who report BVP.