{Reference Type}: Journal Article {Title}: Evaluation of output factors of different radiotherapy planning systems using Exradin W2 plastic scintillator detector. {Author}: Ando Y;Okada M;Matsumoto N;Ikuhiro K;Ishihara S;Kiriu H;Tanabe Y; {Journal}: Phys Eng Sci Med {Volume}: 0 {Issue}: 0 {Year}: 2024 May 16 {Factor}: 7.099 {DOI}: 10.1007/s13246-024-01438-5 {Abstract}: This study aims to evaluate the output factors (OPF) of different radiation therapy planning systems (TPSs) using a plastic scintillator detector (PSD). The validation results for determining a practical field size for clinical use were verified. The implemented validation system was an Exradin W2 PSD. The focus was to validate the OPFs of the small irradiation fields of two modeled radiation TPSs using RayStation version 10.0.1 and Monaco version 5.51.10. The linear accelerator used for irradiation was a TrueBeam with three energies: 4, 6, and 10 MV. RayStation calculations showed that when the irradiation field size was reduced from 10 × 10 to 0.5 × 0.5 cm2, the results were within 2.0% of the measured values for all energies. Similarly, the values calculated using Monaco were within approximately 2.0% of the measured values for irradiation field sizes between 10 × 10 and 1.5 × 1.5 cm2 for all beam energies of interest. Thus, PSDs are effective validation tools for OPF calculations in TPS. A TPS modeled with the same source data has different minimum irradiation field sizes that can be calculated. These findings could aid in verification of equipment accuracy for treatment planning requiring highly accurate dose calculations and for third-party evaluation of OPF calculations for TPS.