{Reference Type}: Journal Article
{Title}: Nanocomposites used in the treatment of skin lesions: a scoping review.
{Author}: Deus WF;Lima CLS;Negreiros ALB;Luz PKD;Machado RDS;Silva GRFD;
{Journal}: Rev Esc Enferm USP
{Volume}: 58
{Issue}: 0
{Year}: 2024
{Factor}: 1.123
{DOI}: 10.1590/1980-220X-REEUSP-2023-0338en
{Abstract}: OBJECTIVE: To map the nanocomposites used in the treatment of skin lesions.
METHODS: A scoping review, according to the Joanna Briggs Institute methodology, carried out on eight databases, a list of references and Google Scholar to answer the question: "Which nanocomposites are used as a cover for the treatment of skin lesions?". Two independent reviewers selected the final sample using inclusion/exclusion criteria using the EndNoteĀ® and Rayyan programs. Data was extracted using an adapted form and reported using the PRISMA checklist extension, and the protocol was registered in the Open Science Framework (OSF).
RESULTS: 21 articles were selected, with nanofibers, nanogels and nanomembranes as the nanocomposites described in wound healing, alone or in association with other therapies: negative pressure and elastic. Silver nanomaterials stand out in accelerating healing due to their antimicrobial and anti-inflammatory action, but caution should be exercised due to the risk of cytotoxicity and microbial resistance.
CONCLUSIONS: Nanocomposites used in wound treatment are effective in accelerating healing and reducing costs, and the addition of bioactives to nanomaterials has added extra properties that contribute to healing.