{Reference Type}: Case Reports
{Title}: [A rare cause of hypercorticism: ACTH-secreting pheochromocytoma (a case report)].
{Author}: Rifai K;Toulali F;Iraqi H;Ettaik M;Gharbi MEH;
{Journal}: Pan Afr Med J
{Volume}: 47
{Issue}: 0
{Year}: 2024
暂无{DOI}: 10.11604/pamj.2024.47.88.36616
{Abstract}: Ectopic ACTH-secreting pheochromocytoma is a very rare cause of Cushing´s syndrome, posing diagnostic and therapeutic challenges. We here report the case of a female patient with suspected severe Cushing´s syndrome associated with melanoderma, arterial hypertension resistant to triple therapy and unbalanced diabetes treated with insulin therapy. Biologically, urinary ethoxylated, 24-hour urinary free cortisol and ACTH were very high. Imaging showed a 3.5 cm left adrenal mass. The patient underwent left adrenalectomy after medical preparation, with good clinico-biological outcome. Anatomopathological examination confirmed the diagnosis of pheochromocytoma. This case study highlights the importance of measuring methoxylated derivatives in any patient with ACTH-dependent Cushing´s syndrome associated with an adrenal mass. The aim is to ensure early treatment and avoid life-threatening complications.