{Reference Type}: Journal Article
{Title}: P(V)-Promoted Rh-Catalyzed Highly Regioselective Hydroformylation of Styrenes under Mild Conditions.
{Author}: Ru T;Zhang Y;Wei Q;Zuo S;Jia Z;Chen FE;
{Journal}: Molecules
{Volume}: 29
{Issue}: 9
{Year}: 2024 Apr 28
{Factor}: 4.927
{DOI}: 10.3390/molecules29092039
{Abstract}: Hydroformylation of olefins is widely used in the chemical industry due to its versatility and the ability to produce valuable aldehydes with 100% atom economy. Herein, a hybrid phosphate promoter was found to efficiently promote rhodium-catalyzed hydroformylation of styrenes under remarkably mild conditions with high regioselectivities. Preliminary mechanistic studies revealed that the weak coordination between the Rhodium and the P=O double bond of this pentavalent phosphate likely induced exceptional reactivity and high ratios of branched aldehydes to linear products.