{Reference Type}: Case Reports
{Title}: Diffuse type gastric adenocarcinoma with atypical presentation: A case report.
{Author}: Edwin G;Mbishi Y;Zerd F;Komanya F;Alphonce B;Sindato E;
{Journal}: Clin Case Rep
{Volume}: 12
{Issue}: 5
{Year}: 2024 May
暂无{DOI}: 10.1002/ccr3.8849
{Abstract}: <B>UNASSIGNED: </B>Gastric adenocarcinoma can present uncommonly. This emphasizes the need for intensified vigilance in the absence of typical gastrointestinal symptoms, particularly in areas where infectious diseases are common.<BR><B>UNASSIGNED: </B>Gastric adenocarcinoma, a common advanced-age global malignancy is typically associated with abdominal symptoms. However, atypical presentations such as back pain and respiratory distress particularly in younger patients represent diagnostic challenges. We present a case of a late-30s male who presented initially with back pain, shortness of breath, and constitutional symptoms. A diagnosis of tuberculosis was established presumptively with immediate initiation of treatment. Later on, he presented with abdominal pain and intractable vomiting. Oesophagoduodenoscopy (OGD), tissue histology, and immunohistochemistry confirmed a diffuse type gastric adenocarcinoma. He died as a result of complications from an advanced disease. This particular instance emphasizes the importance of maintaining a high index of skepticism even in atypical presentations, as well as the significance of prompt OGD alongside potential genetic testing if any. Gastric adenocarcinoma should be contemplated by clinicians in a variety of clinical scenarios, especially when handling younger patients from settings with limited resources to facilitate timely diagnosis and effective treatment.