{Reference Type}: Case Reports {Title}: A rare posterior mediastinal mass: chordoma. {Author}: Willatt LFS;Wollheim MH;Ehrsam JP;Bode-Lesniewska B;Woernle C;Schoeb O;Inci I; {Journal}: J Surg Case Rep {Volume}: 2024 {Issue}: 5 {Year}: 2024 May 暂无{DOI}: 10.1093/jscr/rjae299 {Abstract}: A 72-year-old female presented with 2 years of pro-gradient pain in the upper thoracic spine radiating to the left arm and leg. MRI revealed a 2.7 × 2.0 × 12 cm paravertebral mass at T2/T3, extending into the foraminal and epidural nerves with extensive dural sac contact in the left hemithorax. The removed tumour was surprisingly soft for a schwannoma or chordoma. However, after the surgery, histopathology revealed the presence of brachyury protein (T-box transcription factor T), which is characteristic of a chordoma. While chordomas are extremely rare, it is important that they are kept in mind for the differential diagnosis of a posterior mediastinal mass. Successful treatment can only be achieved through a complete en bloc resection. This can often be complex due to their location along the spine. This case report aims to highlight the features and treatment of this rare disease.