{Reference Type}: Case Reports
{Title}: Pregnancy-associated atypical hemolytic uremic syndrome. Case report.
{Author}: Barrera-Hoffmann C;Mariaca-Ortíz Y;Ruiz-Villa JG;Cuevas-Cruz LE;López-Mendoza MDR;Briones-Garduño JC;
{Journal}: J Obstet Gynaecol Res
{Volume}: 50
{Issue}: 7
{Year}: 2024 Jul 9
{Factor}: 1.697
{DOI}: 10.1111/jog.15958
{Abstract}: Pregnancy-associated atypical hemolytic uremic syndrome (P-aHUS) is a rare disease. There are only few reports in the literature, and most are in the puerperium period. It is a thrombotic microangiopathy (TMA) characterized for microangiopathic hemolytic anemia, thrombocytopenia, and renal dysfunction. We report the case of a pregnant patient at 26.3 gestation weeks, who developed clinical features of TMA, neurological alterations, and septic shock; then after fetus and placental delivery, no clinical improvement was observed; a diagnostic protocol was performed due to suspicion of P-aHUS, showing improvement after the plasma exchange sessions and eculizumab. We present here a brief review of the case since it is an entity that needs to be suspected during pregnancy when TMA features and requires an immediate diagnosis to provide timely treatment.