{Reference Type}: Case Reports
{Title}: Crystalline keratopathy secondary to the use of ciprofloxacin after cataract surgery with confirmation by histopathological study: A case report and review of the literature.
{Author}: García-Uribe PA;Preciado M;
{Journal}: Arch Soc Esp Oftalmol (Engl Ed)
{Volume}: 99
{Issue}: 6
{Year}: 2024 Jun 6
暂无{DOI}: 10.1016/j.oftale.2024.05.001
{Abstract}: <B>OBJECTIVE: </B>To report the case of a 75-year-old patient who presented crystalline keratopathy secondary to the use of topical ciprofloxacin with histopathological verification, after cataract surgery without complications.<BR><B>METHODS: </B>Case report with clinical and photographic follow-up, as well as slides with samples of epithelium and crystalline deposits.<BR><B>RESULTS: </B>Corneal deposits resolved after drug suspension, topical lubricant change, and subsequent surgical debridement. The histopathological examination reported epithelial cells and basophilic particles compatible with drug precipitates.<BR><B>CONCLUSIONS: </B>Crystalline keratopathy is a condition in which crystals of various kinds are deposited in the corneal epithelium and/or in the anterior stroma. It may have an infectious, pharmacological cause or, in rarer cases, corneal dystrophies. Certain factors such as a previous epithelial defect, systemic pathology with diabetes mellitus, ocular surgery and previous dry eye can favor the deposition of ciprofloxacin leading to the formation of a keratopathy.