{Reference Type}: Journal Article {Title}: Prospectives and challenges of nano-tailored biomaterials-assisted biological molecules delivery for tissue engineering purposes. {Author}: El-Nablaway M;Rashed F;Taher ES;Foda T;Abdeen A;Abdo M;Fericean L;Ioan BD;Mihaela O;Dinu S;Alexandru CC;Taymour N;Mohammed NA;El-Sherbiny M;Ibrahim AM;Zaghamir DE;Atia GA; {Journal}: Life Sci {Volume}: 349 {Issue}: 0 {Year}: 2024 Jul 15 {Factor}: 6.78 {DOI}: 10.1016/j.lfs.2024.122671 {Abstract}: Nano carriers have gained more attention for their possible medical and technological applications. Tailored nanomaterials can transport medications efficiently to targeted areas and allow for sustained medication discharge, reducing undesirable toxicities while boosting curative effectiveness. Nonetheless, transitioning nanomedicines from experimental to therapeutic applications has proven difficult, so different pharmaceutical incorporation approaches in nano scaffolds are discussed. Then numerous types of nanobiomaterials implemented as carriers and their manufacturing techniques are explored. This article is also supported by various applications of nanobiomaterials in the biomedical field.