{Reference Type}: Journal Article
{Title}: Plantar vein thrombosis: 17-year longitudinal study of consecutive patients from a Swiss academic center.
{Author}: Serifi M;Kaufmann PA;Fumagalli RM;Kobe A;Kucher N;Barco S;
{Journal}: Res Pract Thromb Haemost
{Volume}: 8
{Issue}: 3
{Year}: 2024 Mar
{Factor}: 5.953
{DOI}: 10.1016/j.rpth.2024.102396
{Abstract}: <B>UNASSIGNED: </B>Plantar vein thrombosis (PVT) is a rare condition. Less than 50 cases have been described in the literature. Evidence from interventional and observational studies is sparse or lacking.<BR><B>UNASSIGNED: </B>To describe a consecutive cohort of patients diagnosed with PVT at a single academic institution over the past 17 years.<BR><B>UNASSIGNED: </B>We searched medical charts from patients managed at the University Hospital Zurich between 2005 and 2022. PVT was detected through sonography (eg, in the presence of a noncompressible deep vein) and/or magnetic resonance (eg, a vein with a filling defect on non-contrast-enhanced or contrast-enhanced imaging). The study was approved by the local ethics commission.<BR><B>UNASSIGNED: </B>We identified 45 patients who had been assessed for PVT. After manual check of these cases, we selected 16 patients with a confirmed, objective diagnosis. Median age was 62 (25th-75th percentiles, 46-73) years, and 9 (56%) patients were women. All patients were symptomatic, usually reporting local pain in the foot (100%) and swelling (67%). The most frequent risk factors were cancer (n = 6; 38%) and prior deep vein thrombosis (n = 4; 25%). Overall, 80% of patients received oral anticoagulation and 20% received parenteral anticoagulation for a median of 90 days. Over a median follow-up of 17 months, 2 (12.5%) recurrent venous thromboembolism events were recorded following the discontinuation of anticoagulation. Index vein recanalization occurred in all 15 survivors. One patient died from cancer 2 years after PVT diagnosis.<BR><B>UNASSIGNED: </B>We provided initial information on the clinical characteristics, treatment, and course of PVT, which partly resembles that of distal deep vein thrombosis.