{Reference Type}: Case Reports
{Title}: Extracranial Hypoglossal Schwannoma: Case Report and Literature Review.
{Author}: Derka S;Ebeling M;Pietzka S;Vairaktari G;Stavrianos S;Schramm A;Sakkas A;
{Journal}: In Vivo
{Volume}: 38
{Issue}: 3
{Year}: 2024 May-Jun
{Factor}: 2.406
{DOI}: 10.21873/invivo.13596
{Abstract}: <B>BACKGROUND: </B>Schwannomas are solitary neurogenic tumors originating from the myelin sheath of peripheral nerves. Extracranial hypoglossal schwannomas comprise <5% of all head and neck schwannomas and can mimic submandibular salivary gland tumors.<BR><B>METHODS: </B>We report the diagnostic imaging, surgical treatment, and histopathological findings of a rare case of extracranial schwannoma of the hypoglossal nerve in a 73-year-old female, presented with an asymptomatic swelling in the left submandibular region that had been persisted for approximately three years.<BR><B>CONCLUSIONS: </B>Accurate diagnosis of this rare clinical entity requires comprehensive diagnostics. The optimal therapeutic strategy is nerve-sparing surgical excision, although it can be challenging.