{Reference Type}: Case Reports
{Title}: Anti-GBM disease in pregnancy.
{Author}: Kafagi AH;Li AS;Jayne D;Brix SR;
{Journal}: BMJ Case Rep
{Volume}: 17
{Issue}: 4
{Year}: 2024 Apr 30
暂无{DOI}: 10.1136/bcr-2023-257767
{Abstract}: We present the case of a pregnant woman in her 20s who presented in her second trimester with severe pulmonary haemorrhage and dialysis-dependent acute kidney failure due to antiglomerular basement membrane (GBM) disease. Responding to therapy, she recovered kidney function and delivered a baby. During her pregnancy, she developed cytomegalovirus viraemia, gestational diabetes and pre-eclampsia. Here, we report the first combined use of cyclophosphamide, rituximab and intensified plasma exchange in anti-GBM disease in pregnancy, allowing minimal exposure to cytotoxic medication, resulting in live birth and dialysis independence.