{Reference Type}: Case Reports
{Title}: Three Cases of Chemical Burns Caused Due to Dimethyl Sulfate Poisoning.
{Author}: Mizuta S;Miyakoshi T;Matsui K;Nakayama Y;Koshida Y;
{Journal}: Cureus
{Volume}: 16
{Issue}: 3
{Year}: 2024 Mar
暂无{DOI}: 10.7759/cureus.57060
{Abstract}: Dimethyl sulfate (DMS) is a drug widely used as a pharmaceutical and synthetic raw material. On the other hand, it is highly toxic and requires management and treatment as a hazardous substance. A mass outbreak of chemical burns resulting from DMS poisoning occurred at a drug factory. All three patients were brought to our hospital, a tertiary emergency medical facility, several hours after exposure. Their vital signs were stable, with only eye pain and a sore throat. However, after admission, two patients required emergency tracheostomy or endotracheal intubation due to laryngeal edema. Improvement was achieved through the administration of steroids, but a severely injured patient required an extended treatment period. DMS poisoning is rare; however, it can be fatal depending on the exposure concentration. Furthermore, even if the initial symptoms are mild, laryngeal edema may develop later, requiring careful monitoring and appropriate airway interventions.