{Reference Type}: Journal Article
{Title}: Rhinitis Control and Medication Use in a Real-World Sample of Patients With Persistent Rhinitis or Rhinosinusitis: A Community Pharmacy Study.
{Author}: Scheire S;Germonpré S;Mehuys E;Van Tongelen I;De Sutter A;Steurbaut S;Van Hees T;Demarche S;Lahousse L;Gevaert P;Boussery K;
{Journal}: J Allergy Clin Immunol Pract
{Volume}: 12
{Issue}: 7
{Year}: 2024 Jul 25
暂无{DOI}: 10.1016/j.jaip.2024.04.031
{Abstract}: <B>BACKGROUND: </B>Little is known about rhinitis control in real-life, nor about the contribution of treatment-related and patient-related factors.<BR><B>OBJECTIVE: </B>This study aimed to examine the level of rhinitis control and rhinitis medication utilization in patients with persistent rhinitis and to identify predictors of rhinitis control.<BR><B>METHODS: </B>A cross-sectional observational study was conducted in patients with persistent rhinitis recruited in community pharmacies. Participants completed the Rhinitis Control Assessment Test, a questionnaire on patient/rhinitis characteristics, and rhinitis medication use. A visual analog scale for nasal symptoms was also completed. Pharmacy dispensing data were used to calculate adherence to intranasal glucocorticoids. Nasal spray technique was evaluated using a standardized checklist. Predictors of rhinitis control were explored using a linear regression model.<BR><B>RESULTS: </B>A total of 1,514 patients, recruited in 215 pharmacies, participated in the study (mean age 48.7 y, 62% female). Almost 60% exhibited suboptimal rhinitis control (Rhinitis Control Assessment Test ≤ 21 of 30). A 50-mm cut-off on the visual analog scale yielded 78.1% sensitivity to identify suboptimal rhinitis control. Participants most frequently used intranasal glucocorticoids (55.6%) and intranasal decongestants (47.4%). Only 10.3% of current nasal spray users demonstrated perfect technique. More than half (54.8%) of glucocorticoid users were identified as underadherent. Female sex, self-reported nasal hyperreactivity, active asthma, and use of oral/intranasal decongestants or nasal saline were identified as predictors of worse rhinitis control.<BR><B>CONCLUSIONS: </B>Suboptimal rhinitis control was common in this real-life sample of persistent rhinitis patients. Improving use of rhinitis medication may be key to increase disease control.