{Reference Type}: Journal Article
{Title}: Protective Efficacy of Lyophilized Vesicular Stomatitis Virus-Based Vaccines in Animal Model.
{Author}: Salawudeen A;Soule G;Tailor N;Klassen L;Audet J;Sloan A;Deschambault Y;Safronetz D;
{Journal}: Emerg Infect Dis
{Volume}: 30
{Issue}: 5
{Year}: 2024 May
{Factor}: 16.126
{DOI}: 10.3201/eid3005.231248
{Abstract}: We evaluated the in vitro effects of lyophilization for 2 vesicular stomatitis virus-based vaccines by using 3 stabilizing formulations and demonstrated protective immunity of lyophilized/reconstituted vaccine in guinea pigs. Lyophilization increased stability of the vaccines, but specific vesicular stomatitis virus-based vaccines will each require extensive analysis to optimize stabilizing formulations.