{Reference Type}: Case Reports {Title}: Guillain-Barre syndrome following scrub typhus: a case report and literature review. {Author}: Hu S;Lin Z;Liu T;Huang S;Liang H; {Journal}: BMC Neurol {Volume}: 24 {Issue}: 1 {Year}: 2024 Apr 25 {Factor}: 2.903 {DOI}: 10.1186/s12883-024-03645-9 {Abstract}: BACKGROUND: Scrub typhus is an acute infectious disease caused by Orientia tsutsugamushi. Guillain-Barre syndrome (GBS) is an autoimmune-mediated peripheral neuropathy with a frequent history of prodromal infections, but GBS associated with scrub typhus is very rare.
METHODS: We report a 51-year-old male patient who developed dysarthria and peripheral facial paralysis following the cure of scfrub typhus. CSF examination and electrophysiological findings suggested a diagnosis of GBS. After treatment with intravenous immunoglobulin, the patient's neurological condition improved rapidly.
CONCLUSIONS: Scrub typhus infection is likely to be a potential predisposing factor in GBS, while scrub typhus-associated GBS has a favorable prognosis.