{Reference Type}: Journal Article
{Title}: Comparison of Non-ephedrine Constituents from Ephedra Plants Cultivated in Japan.
{Author}: Hayashi K;Miyao Y;Matsui H;Yamaura T;Tanaka K;Baba M;Hayashi H;
{Journal}: Chem Pharm Bull (Tokyo)
{Volume}: 72
{Issue}: 4
{Year}: 2024
{Factor}: 1.903
{DOI}: 10.1248/cpb.c24-00043
{Abstract}: Ephedra plants, the main components of which are ephedrine alkaloids, are used as traditional medicines in Eastern Asian countries. In this study, we isolated non-ephedrine constituents from various Ephedra plant species cultivated in Japan. HPLC analysis suggested that kynurenic acid and its derivatives accumulated in a wide range of Ephedra plant species. Furthermore, a large amount of (2R,3S)-O-benzoyl isocitrate has been isolated from E. intermedia. This study suggests that Ephedra plants have diverse non-ephedrine constituents.