{Reference Type}: Review
{Title}: [Anticancer effect of parasites and its underlying mechanisms: a review].
{Author}: Zhang Y;Ding X;Dai Y;
{Journal}: Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
{Volume}: 36
{Issue}: 1
{Year}: 2023 Dec 1
暂无{DOI}: 10.16250/j.32.1374.2023074
{Abstract}: Both parasitic diseases and cancers are disorders that seriously threaten human health. A strong correlation has been recently found between parasitic infections and cancers, and multiple species of parasites and their derived products have shown effective to suppress cancer development, progression and metastasis. Therefore, deciphering the interaction among parasites, cancers and hosts not only provides new insights into the development of cancer therapy, but also provides the basis for screening of parasites-derived active anticancer molecules. This review summarizes the latest advances in the anticancer activity of parasites and underlying mechanisms.<BR>［摘要］ 寄生虫病和癌症均为严重危害人类健康的疾病。近年来研究发现, 寄生虫感染与肿瘤间关系密切, 多种寄生虫 感染及其来源产物能够抑制癌症发生、发展与转移, 显示了较好抗癌症潜能。因此, 充分解析寄生虫、癌症与宿主间的相 互作用, 不仅可以为癌症治疗领域研究开拓新的思路, 而且可为寄生虫来源抗癌症活性分子筛选奠定基础。本文围绕寄 生虫的抗癌症效应及其潜在机制等方面的最新研究进展作一综述。.