{Reference Type}: Journal Article
{Title}: Assessment of Platelet-Rich Plasma Alone and Platelet-Rich Plasma Combined with Bioactive Glass in the Management of Intrabony Defect.
{Author}: Parihar AS;Preethanath RS;Khan N;Mohapatra A;Reshma AP;Seshadri PR;Awinashe MV;
{Journal}: J Pharm Bioallied Sci
{Volume}: 16
{Issue}: 0
{Year}: 2024 Feb
暂无{DOI}: 10.4103/jpbs.jpbs_1100_23
{Abstract}: <B>UNASSIGNED: </B>To assess the function of platelet-rich plasma (PRP) both only and in combination with bioactive glass in intrabony defects.<BR><B>UNASSIGNED: </B>Twenty patients were split into two groups with 10 samples each: group I with PRP alone, whereas group II was done with PRP in addition to bioactive glass. Following local anesthesia, full-thickness mucoperiosteal flaps were elevated in the afflicted site, the defect was debrided, and root planning with curettes was performed. Irrigation was then used while in group II- PRP along with bone graft (BG) preservationwas done. Suturing in group I was contained. At day 0 (baseline) and 6 months after surgery, the clinical parameters for probing depth, clinical attachment stage, and radiographic assessment were noted for both groups.<BR><B>UNASSIGNED: </B>When comparing both groups, there was no statistically considerable variation. However, the intragroup comparison for pocket depth and clinical attachment level between baseline and 6 months was significant. Radiographic bone level was not considerably dissimilar across groups; however, it was significantly different between groups.<BR><B>UNASSIGNED: </B>Reduced probing depth, higher clinical attachment level, and radiographic evidence of bone fill are clinical outcome measures that are associated with effective regenerative therapy.