{Reference Type}: Journal Article
{Title}: High Efficacy of Ivermectin for Strongyloidiasis Treatment.
{Author}: Sengthong C;Pinlaor S;Yingklang M;Haonon O;Jantawong C;Pinlaor P;Sithithaworn P;Hongsrichan N;
{Journal}: Am J Trop Med Hyg
{Volume}: 110
{Issue}: 5
{Year}: 2024 May 1
{Factor}: 3.707
{DOI}: 10.4269/ajtmh.23-0645
{Abstract}: Infection with Strongyloides stercoralis is often asymptomatic but can be life-threatening in immunocompromised patients, which can be prevented by ivermectin (IVM) treatment. The efficacy of IVM has been reported to have lessened over time in some regions as a consequence of prolonged use and mass treatment campaigns. Ivermectin has been used in Thailand for more than a decade; therefore, we investigated the efficacy of a single dose (200 µg/kg) of IVM against in asymptomatic strongyloidiasis in northeastern Thailand. Fecal samples were collected before and 2 weeks after treatment and were analyzed for the presence of Strongyloides using a modified agar plate culture and the formalin-ethyl acetate concentration technique. Our results showed that single-dose IVM treatment successfully eliminated S. stercoralis infection in asymptomatic individuals in the endemic area with a 100% cure rate, indicating the high efficacy of IVM treatment in strongyloidiasis in northeast Thailand.