{Reference Type}: Multicenter Study
{Title}: Clinical manifestation, lifestyle, and treatment patterns of chronic erosive gastritis: A multicenter real-world study in China.
{Author}: Yang YY;Li KM;Xu GF;Wang CD;Xiong H;Wang XZ;Wang CH;Zhang BY;Jiang HX;Sun J;Xu Y;Zhang LJ;Zheng HX;Xing XB;Wang LJ;Zuo XL;Ding SG;Lin R;Chen CX;Wang XW;Li JN;
{Journal}: World J Gastroenterol
{Volume}: 30
{Issue}: 9
{Year}: 2024 Mar 7
{Factor}: 5.374
{DOI}: 10.3748/wjg.v30.i9.1108
{Abstract}: BACKGROUND: Although chronic erosive gastritis (CEG) is common, its clinical characteristics have not been fully elucidated. The lack of consensus regarding its treatment has resulted in varied treatment regimens.
OBJECTIVE: To explore the clinical characteristics, treatment patterns, and short-term outcomes in CEG patients in China.
METHODS: We recruited patients with chronic non-atrophic or mild-to-moderate atrophic gastritis with erosion based on endoscopy and pathology. Patients and treating physicians completed a questionnaire regarding history, endoscopic findings, and treatment plans as well as a follow-up questionnaire to investigate changes in symptoms after 4 wk of treatment.
RESULTS: Three thousand five hundred sixty-three patients from 42 centers across 24 cities in China were included. Epigastric pain (68.0%), abdominal distension (62.6%), and postprandial fullness (47.5%) were the most common presenting symptoms. Gastritis was classified as chronic non-atrophic in 69.9% of patients. Among those with erosive lesions, 72.1% of patients had lesions in the antrum, 51.0% had multiple lesions, and 67.3% had superficial flat lesions. In patients with epigastric pain, the combination of a mucosal protective agent (MPA) and proton pump inhibitor was more effective. For those with postprandial fullness, acid regurgitation, early satiety, or nausea, a MPA appeared more promising.
CONCLUSIONS: CEG is a multifactorial disease which is common in Asian patients and has non-specific symptoms. Gastroscopy may play a major role in its detection and diagnosis. Treatment should be individualized based on symptom profile.