{Reference Type}: Preprint
{Title}: Bicuspid Aortic Valve Disease With Early Onset Complications: Characteristics And Aortic Outcomes.
{Author}: Selbst MA;Laughlin MK;Ward CR;Michelena H;Sabate-Rotes A;Bianco L;De Backer J;Mosquera LM;Yetman AT;Bissell MM;Andreassi MG;Foffa I;Hui DS;Caffarelli A;Kim YY;Guo D;Citro R;De Marco M;Tretter JT;Morris SA;McBride KL;Body SC; ;Prakash SK;
{Journal}: medRxiv
{Volume}: 0
{Issue}: 0
{Year}: 2024 Mar 13
暂无{DOI}: 10.1101/2024.03.11.24304079
{Abstract}: Bicuspid aortic valve (BAV) is the most common congenital heart malformation in adults but can also cause childhood-onset complications. In multicenter study, we found that adults who experience significant complications of BAV disease before age 30 are distinguished from the majority of BAV cases that manifest after age 50 by a relatively severe clinical course, with higher rates of surgical interventions, more frequent second interventions, and a greater burden of congenital heart malformations. These observations highlight the need for prompt recognition, regular lifelong surveillance, and targeted interventions to address the significant health burdens of patients with early onset BAV complications.