{Reference Type}: Journal Article
{Title}: Tumor-like Lesions in Primary Angiitis of the Central Nervous System: The Role of Magnetic Resonance Imaging in Differential Diagnosis.
{Author}: Zedde M;Napoli M;Moratti C;Pavone C;Bonacini L;Di Cecco G;D'Aniello S;Grisendi I;Assenza F;Boulouis G;Nguyen TN;Valzania F;Pascarella R;
{Journal}: Diagnostics (Basel)
{Volume}: 14
{Issue}: 6
{Year}: 2024 Mar 14
{Factor}: 3.992
{DOI}: 10.3390/diagnostics14060618
{Abstract}: Primary Angiitis of the Central Nervous System (PACNS) is a rare disease and its diagnosis is a challenge for several reasons, including the lack of specificity of the main findings highlighted in the current diagnostic criteria. Among the neuroimaging pattern of PACNS, a tumefactive form (t-PACNS) is a rare subtype and its differential diagnosis mainly relies on neuroimaging. Tumor-like mass lesions in the brain are a heterogeneous category including tumors (in particular, primary brain tumors such as glial tumors and lymphoma), inflammatory (e.g., t-PACNS, tumefactive demyelinating lesions, and neurosarcoidosis), and infectious diseases (e.g., neurotoxoplasmosis). In this review, the main features of t-PACNS are addressed and the main differential diagnoses from a neuroimaging perspective (mainly Magnetic Resonance Imaging-MRI-techniques) are described, including conventional and advanced MRI.