{Reference Type}: Review {Title}: Valvar bypass surgery to ameliorate persistent lower limb edema caused by post-thrombotic syndrome: a case report and literature review. {Author}: Wang Y;Zhao L;Zhang J;Du Y;Chen J;Wu Y; {Journal}: J Cardiothorac Surg {Volume}: 19 {Issue}: 1 {Year}: 2024 Mar 21 {Factor}: 1.522 {DOI}: 10.1186/s13019-024-02601-5 {Abstract}: Obstruction and/or reflux compromise during venous emptying can facilitate different pathophysiologies in chronic venous insufficiency (CVI). We present a patient with persistent lower limb CVI edema caused by post-thrombotic syndrome (PTS), who responded well to femoral vein valve therapy via axillary vein bypass after unsuccessful valvuloplasty, and led a normal life. During a 12 month observation period, bridging vessels completely restored original anatomical structures. In a literature study, no similar surgeries were reported, but we show that this operation may be feasible in selected patients.