{Reference Type}: Journal Article
{Title}: Association between a low-risk COVID-19 extracorporeal membrane oxygenation criteria and mortality: A retrospective study.
{Author}: Gostyuzhev I;Mohamed A;Freiberger-O'Keefe CE;Haines MM;Kozinn JB;
{Journal}: Int J Artif Organs
{Volume}: 47
{Issue}: 4
{Year}: 2024 Apr 20
{Factor}: 1.631
{DOI}: 10.1177/03913988241239198
{Abstract}: <B>UNASSIGNED: </B>Our study aimed to compare the outcomes of COVID-19 patients who met a low-risk inclusion criteria for veno-venous extra corporeal membrane oxygenation (VV ECMO) with those who did not meet criteria due to higher risk but were subsequently cannulated.<BR><B>UNASSIGNED: </B>This was a retrospective observational cohort study that included adult patients who were placed on VV ECMO for COVID-19 related acute respiratory distress syndrome (ARDS) at a tertiary care academic medical center. The primary outcome was the association between the low-risk criteria and mortality. The patients met the criteria if they met EOLIA severe ARDS criteria, no absolute contraindications (age > 60 years, BMI > 55 kg/m2, mechanical ventilation (MV) duration >7 days, irreversible neurologic damage, chronic lung disease, active malignancy, or advanced multiorgan dysfunction), and had three or less relative contraindications (age > 50 years, BMI > 45 kg/m2, comorbidities, MV duration > 4 days, acute kidney injury, receiving vasopressors, hospital LOS > 14 days, or COVID-19 diagnosis > 4 weeks).<BR><B>UNASSIGNED: </B>Sixty-five patients were included from March 2020 through March 2022. Patients were stratified into low-risk or high-risk categories. The median Sequential Organ Failure Assessment score was 7 and the median PaO2/FiO2 ratio was 44 at the time of ECMO cannulation. The in-hospital mortality was 47.8% in the low-risk group and 69.0% in the high-risk group (p = 0.096).<BR><B>UNASSIGNED: </B>There was not a statistically significant difference in survival between low-risk patients and high-risk patients; however, there was a trend toward higher survival in the lower-risk group.