{Reference Type}: Case Reports {Title}: Mosaicplasty in the Treatment of Osteochondral Lesions of the Talus: A Report of Two Cases. {Author}: Barrached M;Tebbaa El Hassali A;Sohaib EM;Abdeljaouad N;Yacoubi H; {Journal}: Cureus {Volume}: 16 {Issue}: 2 {Year}: 2024 Feb 暂无{DOI}: 10.7759/cureus.54345 {Abstract}: Osteochondral damage to the talus is one of the most frequent causes of ankle pain. In contrast to other joints in the lower limb, osteochondral damage of the talus is often attributed to traumatic events. One option of treatment is mosaicplasty, which has proved to be a feasible choice for the treatment of osteochondral lesions of the talus; it has the potential to alleviate ankle pain and facilitate engagement in daily activities as well as sports. We present two different cases of osteochondral lesions of the talus, illustrating how this pathology can present clinically. Both cases involve males with no notable pathological antecedents. The first was the victim of a traffic accident, the second was the victim of a sports accident; they were admitted for the management of chronic ankle pain unimproved by analgesic treatment. Radiological findings revealed a talus osteochondral lesion in both patients, treated with an osteochondral autograft from the homolateral knee. Both patients progressed well, with the resumption of daily activities and sports. The notable result of current research is that mosaicplasty has been shown to have good results in those with large osteochondral lesions who want to return to normal activity.