{Reference Type}: Case Reports
{Title}: HIV-associated nemaline myopathy manifesting as bent spine syndrome.
{Author}: Nasir AZ;Jameson A;
{Journal}: BMJ Case Rep
{Volume}: 17
{Issue}: 3
{Year}: 2024 Mar 12
暂无{DOI}: 10.1136/bcr-2023-258988
{Abstract}: HIV-associated myopathies include HIV-associated polymyositis, inclusion body myositis, diffuse infiltrative lymphocytosis syndrome and sporadic late-onset nemaline myopathy (HIV-NM). HIV-NM typically manifests as a painless, progressive proximal and axial muscle weakness with characteristic histological findings of intracytoplasmic rods, or nemaline bodies, seen in atrophic muscle fibres. HIV-NM presents prior to or shortly after initiation of antiretroviral therapy (ART) and is treated with intravenous immunoglobulin, glucocorticoids or immunosuppression. We present a case of HIV-NM in a patient with well-controlled HIV on decades-long ART with progressive bent spine syndrome, or camptocormia. This case highlights the importance of considering HIV-associated myopathies such as HIV-NM in patients with HIV who present with musculoskeletal complaints.