{Reference Type}: Journal Article {Title}: An innovative 3D hydroxyapatite patient-specific implant for maxillofacial bone reconstruction: A case series of 13 patients. {Author}: Systermans S;Cobraiville E;Camby S;Meyer C;Louvrier A;Lie SA;Schouman T;Siciliano S;Beckers O;Poulet V;Ullmann N;Nolens G;Biscaccianti V;Nizet JL;Hascoët JY;Gilon Y;Vidal L; {Journal}: J Craniomaxillofac Surg {Volume}: 52 {Issue}: 4 {Year}: 2024 Apr 28 {Factor}: 3.192 {DOI}: 10.1016/j.jcms.2024.02.026 {Abstract}: The study aimed to evaluate and discuss the use of an innovative PSI made of porous hydroxyapatite, with interconnected porosity promoting osteointegration, called MyBone Custom® implant (MBCI), for maxillofacial bone reconstruction. A multicentric cohort of 13 patients underwent maxillofacial bone reconstruction surgery using MBCIs for various applications, from genioplasty to orbital floor reconstruction, including zygomatic and mandibular bone reconstruction, both for segmental defects and bone augmentation. The mean follow-up period was 9 months (1-22 months). No infections, displacements, or postoperative fractures were reported. Perioperative modifications of the MBCIs were possible when necessary. Additionally, surgeons reported significant time saved during surgery. For patients with postoperative CT scans, osteointegration signs were visible at the 6-month postoperative follow-up control, and continuous osteointegration was observed after 1 year. The advantages and disadvantages compared with current techniques used are discussed. MBCIs offer new bone reconstruction possibilities with long-term perspectives, while precluding the drawbacks of titanium and PEEK. The low level of postoperative complications associated with the high osteointegration potential of MBCIs paves the way to more extensive use of this new hydroxyapatite PSI in maxillofacial bone reconstruction.