{Reference Type}: Case Reports
{Title}: Primary Splenic Diffuse Large B-Cell Lymphoma: A Case Report and Literature Review of a Rare Condition.
{Author}: Seijari MN;Kaspo S;Alshurafa A;Elfaieg A;Elkourashy SA;
{Journal}: Case Rep Oncol
{Volume}: 17
{Issue}: 1
{Year}: 2024 Jan-Dec
暂无{DOI}: 10.1159/000537780
{Abstract}: <B>UNASSIGNED: </B>Primary splenic lymphoma is a rare lymphoproliferative disorder that involves the spleen, exhibits diverse clinical presentations, and lacks a clear consensus in terms of management strategies.<BR><B>UNASSIGNED: </B>We present the case of a 52-year-old patient with a complex medical history marked by multiple chronic medical conditions. The patient was diagnosed with primary splenic lymphoma, specifically the diffuse large B-cell subtype. Treatment for our patient involved a shortened course of chemotherapy (4 cycles of rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone [R-CHOP] followed by two doses of rituximab) due to issues related to compliance and treatment-related complications. This was followed by consolidative radiotherapy without resorting to splenectomy.<BR><B>UNASSIGNED: </B>Remarkably, despite using a shortened course of R-CHOP, the patient achieved complete resolution, and a positron emission tomography scan conducted at the end of the 6-month posttreatment period confirmed sustained complete remission.