{Reference Type}: Journal Article
{Title}: Ansa Cervicalis External Branch Anastomosis to Restore High Tone Voice in Thyroid Surgery.
{Author}: Miyauchi A;Fujishima M;Masuoka H;Sasaki T;Miya A;Ishisaka T;Adachi S;Kawano S;Matsunaga A;Yamamoto M;Higashiyama T;Ito Y;Onoda N;Kihara M;
{Journal}: Laryngoscope
{Volume}: 134
{Issue}: 8
{Year}: 2024 Aug 7
{Factor}: 2.97
{DOI}: 10.1002/lary.31377
{Abstract}: OBJECTIVE: Injury to the external branch of the superior laryngeal nerve (EBSLN) causes low-pitch voice and voice fatigue, particularly in female subjects, and available treatments are limited. Here, we assess a novel surgical procedure to restore a high-tone voice: ansa cervicalis to EBSLN anastomosis (A-E anastomosis).
METHODS: Between November 2012 and April 2022, 13 patients (12 female) underwent unilateral EBSLN resection and A-E anastomosis, while 20 (16 female) underwent EBSLN resection during thyroid surgery. Patients (4494 women and 1025 men) with normal laryngoscopy scheduled for thyroid surgery served as normal controls. Phonatory function was examined using a Phonation Analyzer PA-1000 preoperatively and intermittently postoperatively.
RESULTS: In patients who underwent A-E anastomosis, high-tone voice pitch decreased significantly postoperatively (673.9-471.5 Hz, p = 0.047), with restoration achieved within 5 months. The mean voice pitch in female patients who underwent A-E anastomosis, EBSLN resection, and controls were 580.4, 522.8, and 682.0 Hz, respectively, indicating a significant decrease in EBSLN resection patients than controls (p = 0.002). The (mean - 1SD) of high-tone voice pitch in female controls was 497 Hz; exceeding this may indicate recovery to a high-tone voice. Overall, 73% (8/11) of A-E anastomosis patients exceeded this value, which was marginally larger than the 43% (6/14) who underwent EBSLN resection. Data on male subjects are limited. There were no cases of adverse functional or cosmetic events.
CONCLUSIONS: A-E anastomosis, a novel simple procedure, restored high-tone voice to some extent without any adverse events and thus warrants further investigation.
METHODS: 3 Laryngoscope, 134:3868-3873, 2024.