{Reference Type}: Journal Article
{Title}: Membranes are functionalized by a proteolipid code.
{Author}: Kervin TA;Overduin M;
{Journal}: BMC Biol
{Volume}: 22
{Issue}: 1
{Year}: 2024 Feb 27
{Factor}: 7.364
{DOI}: 10.1186/s12915-024-01849-6
{Abstract}: Membranes are protein and lipid structures that surround cells and other biological compartments. We present a conceptual model wherein all membranes are organized into structural and functional zones. The assembly of zones such as receptor clusters, protein-coated pits, lamellipodia, cell junctions, and membrane fusion sites is explained to occur through a protein-lipid code. This challenges the theory that lipids sort proteins after forming stable membrane subregions independently of proteins.