{Reference Type}: Case Reports
{Title}: Intrathecal morphine delivery at prepontine cistern to control refractory cancer-related pain: a case report of extensive metastatic and refractory cancer pain.
{Author}: Li Q;Long YL;He YW;Long H;Xiao ZP;Li YL;Yang WZ;Jiang LP;Gao W;Zou C;
{Journal}: BMC Anesthesiol
{Volume}: 24
{Issue}: 1
{Year}: 2024 Feb 26
{Factor}: 2.376
{DOI}: 10.1186/s12871-024-02426-8
{Abstract}: <B>BACKGROUND: </B>Extensive metastatic and refractory cancer pain is common, and exhibits a dissatisfactory response to the conventional intrathecal infusion of opioid analgesics.<BR><B>METHODS: </B>The present study reports a case of an extensive metastatic esophageal cancer patient with severe intractable pain, who underwent translumbar subarachnoid puncture with intrathecal catheterization to the prepontine cistern. After continuous infusion of low-dose morphine, the pain was well-controlled with a decrease in the numeric rating scale (NRS) of pain score from 9 to 0, and the few adverse reactions to the treatment disappeared at a low dose of morphine.<BR><B>CONCLUSIONS: </B>The patient achieved a good quality of life during the one-month follow-up period.