{Reference Type}: Multicenter Study
{Title}: Pityriasis Rubra Pilaris: A Multicentric Case Series of 65 Spanish Patients.
{Author}: Montero-Menárguez J;Amat Samaranch V;Puig Sanz L;Ruiz-Villaverde R;Arias-Santiago S;Larrea García M;Ruiz Genao D;Ferrán M;Schneller-Pavelescu L;Romero Ferreiro C;Rivera Díaz R;
{Journal}: Actas Dermosifiliogr
{Volume}: 115
{Issue}: 8
{Year}: 2024 Sep 22
暂无{DOI}: 10.1016/j.ad.2024.02.019
{Abstract}: <B>BACKGROUND: </B>PRP is a rare entity of unknown etiopathogenesis. Lack of management guidelines makes it a challenge for clinicians.<BR><B>OBJECTIVE: </B>To add our experience to increase evidence about PRP.<BR><B>METHODS: </B>We performed a retrospective, descriptive and multicentric study of 65 patients with PRP, being the largest European case series of patients with PRP.<BR><B>RESULTS: </B>PRP was more frequent in male patients with an average age of 51 years, but erythrodermic forms presented in older patients (average age 61 years). Six (75%) paediatric patients and ten (60%) non-erythrodermic adults controlled their disease with topical corticosteroids. On the contrary, 26 (68%) erythrodermic patients required biologic therapy as last and effective therapy line requiring an average of 6.5 months to achieve complete response.<BR><B>CONCLUSIONS: </B>Our study showed a statistical difference in terms of outcome and response to treatment between children or patients with limited disease and patients who develop erythroderma.