{Reference Type}: Case Reports
{Title}: [Conidiobolomycosis (rhinofacial entomophthoromycosis) in Gabon. About of one case].
{Author}: Ntsame Ngoua S;Iba Ba J;Coniquet S;Moussirou Soumbou G;Boguikouma JB;
{Journal}: Med Trop Sante Int
{Volume}: 3
{Issue}: 4
{Year}: 2023 12 31
暂无{DOI}: 10.48327/mtsi.v3i4.2023.457
{Abstract}: Entomophthoromycosis constitutes a nosological group of subcutaneous mycoses including conidiobolomycosis (rhinofacial form) and basidiobomomycosis (subcutaneous form involving the trunk and the limbs). Conidiobolomycosis is characterized by a progressive nasal and facial deformity giving, in the evolved forms, a "hippopotamus snout". The literature review finds a hundred cases, with a tropism for the humid tropical regions. Methods. We report the observation of a 25-year-old patient, living in the equatorial zone, in the south of Gabon in a humid forest area, presenting a swollen aspect of the face mainly involving the eyelids, the nose and the upper lips.<BR>The diagnosis of entomophthoromycosis was compatible with the histopathological and clinical aspects. The evolution was favorable in terms of facial aesthetics under itraconazole 300 mg/day for 2 months and corticosteroid therapy (bolus of methylprednisone 240 mg/day for 3 days relayed per os at a dose of 0.5 mg/kg/day, i.e. 30 mg/day) of prednisone), maintained for 3 months. The average nasal improvement could not be completed by surgery and the patient was lost to follow-up.<BR>This second observation of conidiobolomycosis in Gabon in the same province makes Ngounié a privileged ecosystem for this affection.